iHeir-FP发泡、油墨专用抗菌剂
发泡塑料、油墨通用添加，抗菌率高达99.99%。
Used in foamed plastics and oily coatings, the antibacterial rate is as high as 99.99%.
iHeir-FP为有机阳离子抗菌剂，可有效抑制金黄色葡萄球菌、大肠杆菌、霉菌、白癣菌、白色念珠菌等有害微生物。iHeir-FP具有好的抗菌防臭功能,可添加于塑料（EVA、PU、PP、PVC、TPR等）中，经发泡加工后是发泡塑料继续产生抗菌防臭效果，由于其是油性体系，也可以用于油墨涂层、手感剂添加。
iHeir-FP is an organic cationic antibacterial agent, which can effectively inhibit harmful microorganisms such as Staphylococcus aureus, Escherichia coli, mold, tinea albicans and Candida albicans. iHeir-FP has good antibacterial and deodorization function. It can be added to plastics (EVA, PU, PP, PVC,TPR, etc.). After foaming, foamed plastics continue to produce antibacterial and deodorization effect. It can also be used for adding ink coating.
理化指标
Physical and chemical indicators
项目名称 Project Name | 指标 Parameter |
形态 Morphology | 透明液体 Transparent liquid |
活性成分(%) Active ingredient | 第四级铵 Quaternary Ammonium Salt |
| pH | 6.5-7 |
比重，g/ml Specific gravity, g/ml | 1.045-1.055 |
闪点 Flash point | 380℃ |
稳定性 Stability | 1.8‐2.4g/cm3 |
分散性 Solvability | 与溶剂以任意比例相溶 Soluble in any proportion with solvent |
作用原理
Action principle
iHeir-FP油性抗菌剂外观为透明液体，具有很高的活性，容易被细菌、病毒所吸附，作用于细菌、真菌、藻类的细胞壁系统或细胞膜系统，与细胞磷脂化合物结合，迅速击穿它们的膜体系，使菌体胞内物质外流，并且抑制某些附于细胞膜的酵素活动，从而抑制了细菌病毒的分裂功能，使细菌病毒丧失繁殖能力，而且聚合物的形成堵塞了微生物的呼吸通道，使微生物窒息而死，从而达到杀抗菌的效果。同时，其高分子聚合物结构使有效活性得以提高，使其杀菌效力大大高于其它一般抗菌剂，而且细菌不易产生耐药性。iHeir-FP油性抗菌剂广谱抗菌，对革兰氏阳性菌，革兰氏阴性菌、真菌和酵母菌均有杀伤能力。
iHeir-FP foaming antibacterial agent is a transparent liquid with high activity. It is easy to be adsorbed by bacteria and viruses. It acts on the cell wall system or cell membrane system of bacteria, fungi and algae, combines with cell phospholipid compounds, quickly breaks down their membrane system, makes the intracellular substance flow out, and inhibits the activities of some enzymes attached to the cell membrane. In addition, the formation of polymer blocks the respiratory channel of microorganisms and suffocates them to death, so as to achieve the bacteria killing effect. At the same time, its high molecular polymer structure can improve its effective activity, which makes its bactericidal efficacy much higher than other general antibacterial agents, and the bacteria are not easy to produce drug resistance. iHeir-FP is a broad-spectrum antibacterial agent, which can kill Gram-positive bacteria, Gram-negative bacteria, fungi and yeasts.
毒理性数据
Toxicological data
iHeir-FP油性抗菌剂可长期使用，毒性很低，对动物进行急性经口毒性试验、急性皮肤刺激试验、小鼠骨髓嗜多染红细胞微核试验、小鼠精子畸形试验、蓄积毒性试验、皮肤变态反应试验等一系列毒性试验，测试结果表明：
iHeir-FP foaming antibacterial agent can be used for a long time with low toxicity. A series of toxicity tests were carried out on animals, such as acute oral toxicity test, acute skin irritation test, micronucleus test of mouse bone marrow polychromatic erythrocytes, sperm deformity test, accumulative toxicity test and skin allergy test.
急性经口毒性试验
小鼠染毒后，未出现中毒症状和死亡，雌雄小鼠经口LD50＞5000mg/kg体重，iHeir-FP属实际无毒级。家兔皮肤刺激试验
iHeir-FP油性抗菌剂对皮肤刺激反应积分均值为0，表明该消毒剂对家兔皮肤属实际无刺激性。微核试验
试验组微核细胞率及PCE/NCE与阴性对照组比差异无显著性，但与阳性对照组比差异有显著性(p＜0.01)，说明该消毒液对小白鼠骨髓嗜多染细胞无致微核作用。小鼠精子畸形试验
该消毒液高、中、低3个剂量组对小鼠精子细胞畸变率分别为1.68、1.77、1.90，阴性对照组畸变率为1.88，各试验组精子细胞畸变率与阴性对照组比差异无显著性(p＜0.05)；阳性对照畸变率为9.80，各试验组精子细胞畸变率与阳性对照组比差异有著性(p＜0.01)。该消毒液对雄性小鼠精子无致畸作用。蓄积毒性试验
给药20天，小鼠未出现死亡，蓄积系数k＞5，按蓄积毒性分级标准[2]，PHMB消毒剂为弱蓄积毒性。皮肤变态反应试验
试验组豚鼠致敏率为0%，未见皮肤变态反庆，说明该消毒剂无致敏作用。
与传统皮肤消毒剂相比，聚六亚甲基双胍复方消毒剂有效使用浓度低，稳定性好，且无毒、无刺激，无致突变作用，无致微核作用，对雄性小鼠精子无致畸作用。有弱蓄积毒性，不引起变态反应。
Acute oral toxicity test
The oral LD50 of male and female mice was more than 5000mg / kg body weight. iHeir-FP belongs to the actual non-toxic level.Skin stimulation test of rabbits
The mean value of the integral of iHeir-FP foaming antibacterial agent to skin stimulation was 0, indicating that the disinfectant was practically non irritating to the skin of rabbits.Micronucleus test
There was no significant difference in the micronucleus cell rate and PCE/NCE ratio between the experimental group and the negative control group, but there was significant difference between the experimental group and the positive control group (P < 0.01), which indicated that the disinfectant had no micronucleus inducing effect on the polychromatic cells of mouse bone marrow.Sperm deformity test in mice
The aberrance rate of sperm cells in the three groups was 1.68, 1.77 and 1.90 respectively, the rate of the negative control group was 1.88 and the difference between the two groups was not significant (P < 0.05); The rate of aberrance of positive control was 9.80, and the difference between the sperm cell aberrations of each experimental group and the positive control group was significant (P < 0.01). The disinfectant had no teratogenic effect on the sperm of male mice.Accumulative toxicity test After 20 days of administration, there was no death in mice, and the accumulation coefficient k > 5. According to the accumulation toxicity grading standard [2], PHMB disinfectant had weak accumulation toxicity.
Skin allergy test
The sensitization rate of guinea pigs in the experimental group was 0%, and there was no skin allergy, indicating that the disinfectant had no sensitizing effect.
Compared with the traditional skin disinfectant, polyhexamethylene biguanide compound disinfectant has low effective use concentration, good stability, no toxicity, no stimulation, no mutagenicity, no micronucleus effect, and no teratogenic effect on male mouse sperm. It has weak accumulative toxicity, which will not cause allergic reaction.
性能特点
Performance characteristics
只需少量添加量即可表现优异的抗菌效果，最高抗菌率可达99.99%。
无毒副作用，对皮肤、粘膜、眼睛无刺激，皮肤对其无过敏。
对光、热稳定；在较宽PH（PH=1～11）范围内稳定。
不会产生细菌耐药性，长久有效。
无色、无味、不挥发，不含重金属、卤素、酚类、醛类物质，对各类表面处理无腐蚀。
Only a small amount of additives can show excellent antibacterial effect, and the highest antibacterial rate can reach 99.99%.
No toxic side effects, no irritation to skin, mucous membrane and eyes, and no skin allergy.
Stable to light and heat; It is stable in a wide range of pH (pH = 1-11).
No bacterial resistance, long-term effect.
colorless, tasteless, non-volatile, free of heavy metals, halogen, phenols, aldehydes, no corrosion to all kinds of surface treatment.
运用领域
Application field
iHeir-FP油性抗菌剂广泛应用于塑料发泡行业、油墨,可添加在发泡材料（PP/PE/PVC/EVA/EPS/PU/硅橡胶）里面一起生产,例如制成具有抗菌的鞋材。
iHeir-FP foaming antibacterial agent can be widely used in plastic foaming industry and printing ink. It can be added into foaming materials (PP / PE / PVC / EVA / EPS / PU / silicone rubber) for production, such as make into shoes with antibacterial properties.
使用说明
Instructions
iHeir-FP油性抗菌剂可直接在发泡原材料中直接添加，其添加形式跟色粉加入一样,均匀搅拌以后按照正常的流程操作，建议添加量为1%-2%（按照发泡塑料的总重量计算）。
iHeir-FP foaming antibacterial agent can be directly added to the foaming raw materials in the same way as the toner. After uniform mixing,operate according to the normal procedure. The recommended addition amount is 1% – 2% (calculated according to the total weight of the foaming plastic).
包装、贮存和保质期
Packaging, Storage and shelf life
iHeir-FP油性抗菌剂以25kg包装,也可根据客户实际需求包装。请将iHeir-FP油性抗菌剂放在阴凉干燥的地方，使用完毕后应尽快密封包装，该产品在正常的包装下一年内均有效。
iHeir-FP foaming antibacterial agent is packed in 25kg, which can be packed according to the actual demands of customers.Please keep the iHeir-FP foaming antibacterial agent in a cool and dry place.The package should be sealed as soon as possible after use, and the shelf life is 1 year under the normal package condition.
